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Understanding Treatment


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Treatment with KISQALI

KISQALI® (ribociclib) is a prescription medicine that's taken with hormone therapy to treat postmenopausal women who are living with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative metastatic breast cancer.

KISQALI and Hormone Therapy Work Together

To understand how KISQALI works with hormone therapy, it’s important to also understand the role that hormones play in causing your type of cancer cells to grow and divide.


Together, KISQALI and hormone therapy work to help delay disease progression:

  • KISQALI is a targeted treatment that blocks, or interferes with, substances that play a role in cancer cell growth. KISQALI can also affect healthy cells
  • Hormone therapy works by stopping or reducing the production of hormones, like estrogen
  • Hormones, like estrogen, activate CDK4/6 proteins, leading to cell division and tumor growth


Click here to learn more about results with KISQALI.


Take a look at the visual below to see how KISQALI + hormone therapy work in the body.

KISQALI® (ribociclib) Mechanism of Action KISQALI® (ribociclib) Mechanism of Action