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Living Longer is Possible—and Proven
Overall Survival Results
KISQALI is Proven to Help Women Live Longer
KISQALI® (ribociclib) is the first and only medication in its class that's proven in multiple clinical trials to help women live longer with HR+, HER2- metastatic breast cancer (mBC). Now, women with mBC—confident, informed, and determined—are learning what it means to live longer. They call themselves the Thrivers, and you're about to see why.
Results for Premenopausal Women Taking KISQALI + a Nonsteroidal Aromatase Inhibitor (NSAI) + Goserelin
KISQALI was studied in a clinical trial dedicated exclusively to younger women. The median age was 44 years (range 25 to 58). 495 women were treated with KISQALI + an NSAI (i.e. letrozole or anastrozole) + goserelin or an NSAI + goserelin.
Overall survival
In a clinical trial, KISQALI + an NSAI + goserelin extended the length of time women were alive from the start of treatment—also called overall survival (OS). Median OS is the length of time when half of the women were still alive. Median OS was not reached for KISQALI + an NSAI + goserelin (meaning more than half the women were still alive at the time of the analysis) vs a median of 40.7 months for those taking an NSAI + goserelin.
Median progression-free survival
In the same clinical trial, half the women taking KISQALI + an NSAI + goserelin still showed no disease progression after 27.5 months vs 13.8 months for women taking an NSAI + goserelin. Median progression-free survival (PFS) is the length of time when half of the women had not yet progressed.
Proven to shrink tumors
KISQALI + an NSAI + goserelin worked together to shrink tumors in women who had measurable tumors.
Results for Postmenopausal Women Taking KISQALI + Fulvestrant
In a clinical trial with 726 women, 484 were treated with KISQALI + fulvestrant and 242 women were treated with fulvestrant alone.
Overall survival
In a clinical trial, KISQALI + fulvestrant extended the length of time women were alive from the start of treatment—also called overall survival (OS). Median OS is the length of time when half of the women were still alive. Median OS was not reached for KISQALI + fulvestrant (meaning more than half of the women were still alive at the time of the analysis) vs a median of 40 months for those taking fulvestrant alone.
Median progression-free survival
In the same clinical trial, half the women taking KISQALI + fulvestrant still showed no disease progression after 20.5 months vs 12.8 months for women taking fulvestrant alone. Median progression-free survival (PFS) is the length of time when half of the women had not yet progressed.
Proven to shrink tumors
KISQALI + fulvestrant worked together to shrink tumors in women who had measurable tumors.
